https://www.ncbi.nlm.nih.gov › pmc
A General Approach to Testing for Pleiotropy with Rare and Common ...
作者：DJ SchaidGenetic pleiotropy is when a single gene influences more than one trait. ... A formal test of pleiotropy should assume a null hypothesis that one ... 2016 被引用次数：36 —
作者：DJ SchaidThe test for pleiotropy provides strong evidence that the signal of association was driven by a single phenotype. This is confirmed ... 2016 被引用次数：36 —
作者：Z YuanIn simulations, PMR-Egger provides calibrated type I error control for causal effect testing in the presence of horizontal pleiotropic ... 2020 被引用次数：17 —
作者：FJ BoehmWe extend the method of Jiang and Zeng (1995), for testing pleiotropy with a pair of traits, to the case of more than two alleles. 2019 被引用次数：4 —
作者：D RayThe underlying methods, however, are often designed to test the global null hypothesis that there is no association of a genetic variant with ... 2020 被引用次数：7 —