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Arginine metabolism pathway
L-arginine can be metabolized to nitric oxide (NO) by nitric oxide synthase (NOS) and to urea and L-ornithine by arginase. Competition between these pathways for L-arginine in inflammatory sites has been suggested. In experimental glomerulonephritis glomeruli produce nitrite; a major source is macrophages.L-arginine can be metabolized to nitric oxide (NO
nitric oxide (NO
Nitric oxide or Nitrogen monoxide is a chemical compound with chemical formula NO. This gas is an important signaling molecule in the body of mammals including humans and is an extremely important intermediate in the chemical industry. It is also a toxic air pollutant produced by automobile engines and power plants.
https://pubchem.ncbi.nlm.nih.gov › Nitri...
) by nitric oxide synthase (NOS) and to urea and L-ornithine
L-ornithine
Ornithine decarboxylase (ODC) is the primary rate-limiting enzyme for polyamine synthesis. ODC levels are increased in most tissues, including the intestinal mucosa, by growth-promoting agents. This enzyme has a brief half-life of from 5 to 30 min in mammalian tissues and is regulated by its product; putrescine.
by arginase
arginase
The optimum pH of cotyledon arginase was found to be 10.0. This is found to be slightly higher than Evernia prunastri and Soybean axes 5, 20. Liver arginase showed high activity at pH 9.2 (Figure ​ 6).
https://www.ncbi.nlm.nih.gov › articles
. Competition between these pathways for L-arginine in inflammatory sites has been suggested. In experimental glomerulonephritis glomeruli produce nitrite; a major source is macrophages.
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Arginine metabolism. Stable Identifier. R-GGA-187630. Type. Pathway. Species. Gallus gallus ... Arginine is an essential amino acid in chickens.
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by T Pols2021Cited by 1In cells, the breakdown of arginine to ornithine and ammonium ion plus carbon dioxide is coupled to the ...

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